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What OTC pain killers can you safely mix for cross potentiation?

Asked by ETpro (34605points) December 11th, 2010

Excedrin combines aspirin, Tylenol (acetaminophen) and caffeine. Taken together, the analgesics are much more effective than any one alone, even if the single one is taken in larger dosage. The caffeine makes Excedrin or its generics particularly good at relieving headaches, as caffeine alone tends to relieve headache pain.

How about other analgesics such as Motrin (ibuprofen), Aleve (Naproxen sodium), etc. What analgesic cocktails are safe and more effective than any of the constituents taken separately?

I seem to have a tooth that’s abscessing back near where my lower right wisdom tooth used to be. I can feel the fistula on the gum below it, and I can REALLY feel the tooth. What’s safe to take in OTC analgesics to get me through the weekend while my dentist is unavailable? What, if any OTC analgesics should I always avoid mixing?

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