What is your definition of a loser?
It seems to me that there are losers who are losers because of the attitude they have, and then there are losers who are losers for no fault of their own. The former are real losers and even if they start winning, they’ll still be losers. The latter—well, their luck will turn and then they won’t be losers any more.
Examples and stories will be really helpful here. If you could describe someone you know who you think is a loser and then say why. It’ll make a clearer picture.