What can you do to a seed to make it not be able to grow?

Umm, grinder.

Try not planting it.

Wait, are you sabotaging someone’s seeds? Never hurt a man’s seeds.

Simply, a seed will not grow w/out the right conditions. A seed wiil not grow w/out moisture for example.

what is the point of this question?

you could varnish seeds, like watermelon or apple seeds, and then they won’t grow. But needless to say, it’s not that hard to make most seeds not grow. The hard part is usually growing.

This is an awfully involved practical joke to play on your children. Teaching them disappointment early isn’t always the best method.

You could transfect interference RNA to inhibit expression of growth factors.

@nikipedia LOL. Great answer!

Use chemicals, don’t provide the seeds with what they need (air, water, earth), crush the seeds either using ur own brute force or other mechanical means, eat the seats

Soak it in Roundup®

Wear a condom?

we may need some clarification on what kind of seed we are talking about

Are you waiting for the watermelon seed you just swallowed to grow or something?

someone is cheating on their science project

Irradiation?

Also, let it get too old, but that’s unreliable as methods go.

Heat treatment – which is what happens to weed seeds in a good compost pile.

In the spirit of Laureth’s answer; Microwave it.

Fireside, that was too funny. In an (ahem) biblical sense, of course.