General Question

john65pennington's avatar

Vioxx vs. Celebrex. One remains, the other is gone. Why?

Asked by john65pennington (29202points) November 26th, 2010

I have taken Vioxx and Celebrex for arthritis, resulting from past surgeries. Both worked equally well for me. I understand that both medications contain the same ingredients. I also understand that there has been a heart-related death associated with Vioxx and it is no longer available. Question: If both medications do contain the same ingredients, then why was Vioxx taken off the market and Celebrex still remains?

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5 Answers

Seelix's avatar

Are the same ingredients found in both medications in the same proportions? That’s the only reason I can think of, aside from some sort of problem with Vioxx’s parent company.

Edit: according to the Wikipedia article, Merck (Vioxx’s parent company) voluntarily withdrew the drug based on potential heart-related issues. Celebrex is apparently a different drug, which I suppose doesn’t have the same threat.

marinelife's avatar

Apparently, they were different enough that people didn’t have heart attacks and die after taking Celebrex.

crisw's avatar

They aren’t the same drugs, although they are in the same family. Vioxx is rofecoxib and Celebrex is celecoxib. Vioxx was withdrawn by the manufacturer in 2004. Celebrex may have some danger but controlled studies have shown it poses no heart risk at low doses, and may even help heart patients.

jerv's avatar

Celebrex never caused my to pass whole blood out my ass the way Vioxx did so I think that there is more to it than just the heart.

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