Is it faster to transfer between two hard drives if they are daisy chained via Firewire 800 or between them if one drive is hooked up to firewire 800 the other drive is hooked up to USB 2.0?

I ask so many exciting file transfer questions. Moving a large amount of data- which of these methods is faster? I always use firewire because it is faster but does daisy chaining slow it down? If I am moving the data between hard drives the data has to move through the computer to each device correct? Would Firewire still outpace USB 2.0? (Side note: I would love actually if someone would explain what happens- the path of your data- when you are transferring between two daisy chained HDs)