Would a European mp3 play on an American mp3 player?

There’s a specific mp3 I’m looking for that’s not available in any American stores, but I can download it from an online store in the UK. Would an mp3 from the UK still work on my American computer and mp3 player? I am not sure if European countries use different encoding software that would make their mp3 files incompatible with American electronics. I do not want to purchase the mp3 only to get a file that doesn’t work. Can anyone help?