CV joints and failing calipers?

I hit a huge pothole in the winter and feel like I’ve been paying for it every since. I’ve changed my tires several times because of a bent rim. I also began feeling a vibration in my car’s acceleration for sometime but haven’t been able to get it fixed. Then a couple days ago, my brakes went out and despite filling the reservoir with additional fluid, they still didn’t work. I thought that the caliper had failed because there appears to be leakage all over the boot. As I turned the wheel in an effort to get at the caliper, I realized that the CV joint boot was cracked wide open. Is it possible that a failed CV joint has caused a brake failure or are these two seperate systems and I’m just experiencing bad luck? Should I replace the CV joints & calipers on both sides of the car?