What are some terrible things to be cursed with?

I’m writing a book about a girl who is cursed with hurting anybody she touches. She finds that there are other people like her, called sirens, who have different curses. Each curse is different and cause harm to either themselves or other people. I need some ideas to get my imagination going. Besides not being able to touch any living thing besides plants, what would be some terrible curses to live with?
Each idea is appreciated. Thank you!