Would you be able to force yourself to eat more than you normally would?

This question is slightly different take on This Question that I asked earlier.

Suppose they came up with a compound that when added to your favorite food, or even added to food that you don’t like, could cause you to have a good amount of weight loss, but the caveat is, that you would have to eat at least twice the amount of this food that you would normally be physically comfortable eating. You would have to stuff yourself until you were past being full, for the compound to have the effect of weight loss. If you simply ate the same amount that you currently enjoy (even if it’s a lot more than you’d care to admit) you would still gain weight.

Once again, this is all hypothetical. I am unaware of any compounds that when added to Cheetos or Chips Ahoy cookies, if eaten in large quantities, will help you to lose weight.

If there was such a compound, would you be able or willing to eat your delicious snack if you had to consume it past the point of being full? Would it be easier to choke down the food, if the compound was added to a food that you already don’t like, kind of like having to choke down nasty tasting medicine?