Why the characters in the anime are not like the Japaneses?

They speak japanese, have japanese customs, clothes, names.
They are japanese.

No one has these complaints about the Simpsons.

It is a method which allows rapid recognition of certain characters.

The real manifestation of anime characters exist (in the form of cosplaying) in Harajuku District, Japan. There are many Japenese anime with different artstyle that come from different authors so not all anime have the same characters design (which including hair color) and I think that’s what make them unique and interesting.

And the eyes?

In the early 20th century, when Disney started making cartoons, along with others, the eyes were small, and the Japanese felt the eyes were cold and non-inviting. So they make the eyes big to more easily portray the soul of the characters.