Do you read and follow the washing instructions for your individual clothes?

I am catching up with what seems like over two months of folding laundry (was on vacation) and am just noticing that each of my clothes have individual washing instructions, MOST of which require hand washing. Now, I know I don’t have the time or motivation to hand wash all my clothes. But I was wondering if this is a more common practice than I would expect.

So do you pay any attention to those labels on your clothes? Or do they all go in the same washing machine load under the same set of instructions regardless?