Should I sell my grandmother's diamond ring?

I have a beautiful European diamond ring that was my grandmother’s. It’s a really pretty ring, and it’s worth quite a bit (I’ve had it appraised). But, the grandmother who owned it was not the nicest person and she treated my dad (and really all the grandkids) with a great deal of disdain. In other words, I don’t have any sentimental attachments to the ring.

But, it is a “family heirloom.” I suppose I could keep it for my daughter to wear or for my son to give to his fiance one day, but who knows if either one of them will really want it.

That’s why I’m wondering whether or not I should sell it. If it were my mom’s ring, there would be no question because I do have sentimental attachments to her. But, if I sold my grandmother’s ring, I could use the money for some things we need around the house or a new camera lens or a computer. But those things aren’t heirlooms.

So, any advice?