What is your favorite quote of all time?

I want to know what everyone has as a favorite quote? Mine is by Oscar Wilde – “We are all lying in the gutter, but some of us are looking up at the stars” To me that quote speaks so many truths and its been my favorite quote for years. I want to hear a quote that resonates in your mind, something that means something to you or has had a profound effect on your life. Give a little description as to why as well just so everyone can see where your coming from!