Does anyone have experience with legitimate work from home opportunities?

Like nearly 1 in 10 USAmericans, I’m unemployed. I’m in a small town so the options are pretty limited. I’ve seen a lot of ads in the classifieds for different work at home opportunities. However, once I start doing any research on them, I quickly find out that people rarely make money on them or that they are out and out scams. So I ask you fellow fluthers, do you know of a way to make good money from home?