Do you ever have a "Crying Game" moment on Fluther?

Have you ever assumed that someone with an androgynous avatar or screen name is one gender only to discover after some time that they are another? I have had this happen a few times, once just yesterday. Does it change how you feel about or relate to that person? Can you analyze why or in what ways? In both of my instances, it has changed subtly my perceptions of the person and I can’t figure out why. I am very intrigued by this phenomenon. Your thoughts?