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john65pennington's avatar

Why is grapefruit not allowed with Lipitor?

Asked by john65pennington (29192points) September 19th, 2010

I have been taking Lipitor with three heart stents for the past ten years. After all this time, i just noticed a one-liner on the packaging that states: avoid grapefruit, while taking Lipitor. I am not a big grapefruit lover, but i wonder what effect that grapefruit has on Lipitor? Question: If grapefruit has this effect on Lipitor, does it also have the same effect on other heart medications? If so, should we be concerned?

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2 Answers

tedibear's avatar

There is a drug interaction with the grapefruit, making it less effective. Here is a previous discussion on Fluther with some links to information. There may be other people out there with more information; I just happened to remember this question.

zenvelo's avatar

grapefruit is broken down by the same liver enzyme used to breakdown lipitor. Because this prevents full utilization of the medication, you are not getting a proper dosage. Meanwhile you are getting a buildup of lipitor in the blood stream, which will breakdown muscles and possibly damage the kidneys.

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