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In one single dose, how much acetaminophen (Tylenol) does it take to pose a threat of liver damage in a healthy adult?

Asked by ETpro (34605points) February 15th, 2012

The recommendation is no more than 4,000 mg (4 grams) of acetaminophen (Tylenol or Paracetamol) per 24 hour period. But how many milligrams can a single dose contain if you don’t take any more that day? Would 4,000 mgs. be just fine in a single dose if you took no more for days afterward? Or would that be enough to trigger hepatotoxicity?

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