Is it possible to drive to Ghana from Morocco, if so which countries should I avoid or make sure I pass through?

Two male mates of mine, another girl and I (girl) want to drive to Ghana (from the UK but it is easy to get as far as Morocco) but I want to know if there are any major areas I should avoid en route from Morocco to Ghana. We are well traveled but have never been to West Africa and due to the continually changing political situations out there would like to know if there are any areas we really need to steer clear of. Alternatively are there any places we really need to stop off on the way an see too?