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Why is the dosage for some medications based on age rather than weight?

Asked by augustlan (47745points) February 5th, 2013

I’m talking to @mangeons right now, and she’s sick. She’s taking some NyQuil so she can get some sleep, and there isn’t quite enough left in the bottle for a full dose. I told her it’d be fine because the usual dose is meant for anyone over age 12, and she’s tiny.

That’s when it occurred to us to wonder: Why would the dose be the same for her (a 17 year old girl who is 5’2” and 108 lbs) as it is for, say, my husband (who is 6’2” and 230 lbs)?

How can they possibly both receive the same benefits from the medication? How does it work?

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