What tiny physical thing can annoy you like no other?

Ok, today I have stabbed myself twice while sewing and at one time it was pretty deep and made me bleed pretty good but I sucked my sucked my wound and kept sewing because I was determined to just be done with it.

I even hurt my back vacuuming today. But my biggest pet peeve was a tiny bug bite at my wrist. I think it must’ve been an ant bite from working in the yard yesterday. Yesterday I was able to make it stop itching but if anything rubs it, it just bugs me to no end. I finally just put some ointment on it and put a band-aid on it but it has put me in a foul mood all day. Its really sensitive but I believe its because it is so near some veins. I equally hate bug bites on the top of my toes. Especially ant bites.

So it has me wondering if anyone else has something that can physically annoy them like no other?