You novelists here: what is the topic of your novel, and how far does it diverge from your life?

I am having trouble finding a fictional topic that calls to me. Give me an exercise in writing, and I’ll throw together something in an instant. But when it comes to what I want to write about… no clue.

Of course, it has to have something to do with my life, but there are so many parts of my life that could become novels.

Anyway, what’s your topic, and how did you come to it? Is it much different from your life?