Anyone here had issues upgrading to OS X 10.5.6?

I updated my MacBook last night with no problems but have since heard that a lot of people are having issues with it. Now I can’t decide whether to go ahead and do my iMac the normal way through software update, or to download the combo updater and perhaps do it in safe mode, or wait for 10.5.7.

Have you updated? Through software update or combo updater? Any problems?