What is the most prestigious or significant juried photo exhibition you know of?

Research for a novel again. I’m looking for an event (maybe a prize) that would be life-changing for an emerging photographer. Something that would require a huge amount of time, commitment and focus, not just being in the right place at the right time, although that could factor in. When I search Google, I discover too many options! Any pro photographers out there? What is the biggest honor for your profession? Where would you love to be exhibited?