Is it safe to use hand sanitizers about 10 times a day?

I have given up on using soap and water to clean my hands. there is a bottle of Purell or Germx in each room of my house and in both cars. is America becoming a country of germ freaks? i use to wash my hands many times a day, but the sanitizers are so convenient to use, that handwashing is just about extinct. question: the human bodys immune system is a wonderful protectorant against germs and bacteria. does using hand sanitizers hurt our immune system, since sanitizers seem to be taking its place?