Say that a marriage is in trouble, and the one spouse decides to leave the home (that they share); could you prevent that spouse from coming back to the home?

Your marriage is hanging by a thread (and it has been for years). One spouse decides to get up and leave. Their words “I’m leaving”. They pack their stuff and take off. Three days later, they come back.

The next time that it happens (if it does), could you legally change the locks and prevent them from coming back to the house?

I’m clueless when it comes to this sort of stuff. I do know of someone who is going through this, though.