I'm desperately constipated... what can I do to poop?

I’m early in my pregnancy and the anti-nausea medicine I was taking (Zofran) made me constipated. I’ve stopped taking it because I’d rather be nauseated than not poop for another 5 days. But I’m still not going. I’m taking fiber supplements and Colace and trying to eat as many fruits and veggies as possible and nothing is working. I think my poop machine is permanently broken. Are enemas safe for me? Is there anything else I can do? Please help. It’s too late tonight to call my midwife, and I’m on vacation and like an IDIOT I didn’t bring her emergency number with me. I’m not finding anything useful online.