What happens when you grow apart?

Recently, I’ve found that conversations between me and someone I grew up with require a lot of effort. In fact, we basically have nothing to talk about anymore and we couldn’t be more on a separate page in life and perspective (even though we’re close in age). I think it may have always been that way, but we could always find something to talk about… now it’s just… nothing. It feels awkward and forced. Is it possible for one person in a relationship to change so much? (I think I have changed.)