Could you lead a life with no secrets - why (it's the rationale I'm after not the yes/no)

Give a rationale as to why you could or couldn’t live your life without holding back any secrets from anyone.
Definition of secret for this question; thoughts, things about yourself that you tend to keep to yourself. What you really think for example.

Secondary question(s): What do you imagine would happen if you revealed them?
Do you have experiences where revealing a secret was devastating, or examples where what you thought would happen was a huge exaggeration over what actually happened?

Much lurve for longer and complete answers :)