Blending Drama with Comedy in a Web Series?

My friends and I are writing a web series about 6 teens who live in a foster home and it’s going to be a comedy. Of course with the background being a foster home, there’d be drama going on. I was wondering if YOU like it when a web series mixes drama with comedy. I’m debating whether we should write in dramatic endings or occasionally dramatic plotlines to mix with the comedy that comes from the quirky and diverse characters. It’s a series that’d be put on YouTube and I don’t see to many drama/comedy mixes on there. It’s either all comedy or all drama.

Also, do you have any tips?