Are you opposed to buying used clothing from a thrift store?

I know several people that don’t feel comfortable buying/wearing used clothing from a thrift store, even if it’s been washed several times since its previous owner wore it. I personally would have no objection to it, as long as I’ve washed it and know that it is clean.

Would you be open to wearing used clothing, or is there just something about it that would make you uncomfortable? Would you buy other used items, with the exception of clothing?