Do you notice a huge difference between average quality spices, such as McCormick's, and high end, like (I would think) Whole Foods or other organic spices?

I need some ginger and am wondering what other Jellies think of the difference in quality between high end, like Whole Foods, organic or whatever, and “middle of the road” like McCormick’s or other brands that can be found in your average supermarket.

Is there a noticeable difference? Is the price difference worth it?