How can change occur in this family?

How can this person be helped? He is 35 years old and still living with his parents. His day is spent for the most part calming them as they suffer with anxiety disorders and ill health. He now has a girlfriend and his time is spread evenly over helping his parents, which includes, taking them to the doctor if need be, collecting their prescriptions, talking them down from high anxiety states, cutting their lawn, painting and generally being a caregiver.

They are both able to drive and also are not at all elderly or frail. His mother seems to be the one with the most anxiety. She will not drive although has a licence, will not visit people on her own or go out.

When he does stay at his girlfriends house (my friend) he is phoned in the middle of the night since both parents are in a panic. He very rarely attempts to stay overnight with her due to this I see things as getting worse since the father has been diagnosed with 1st Stage Cancer, although prognosis is excellent.

He has never had a full time relationship in the normal sense as he is constantly seeing to his parents needs. The parents would never seek help in this matter. They do have family members and friends and friendly neighbors but will not use these resources as they prefer to ‘use’ their son.

Any insights appreciated, or similar experiences where this was managed effectively would be appreciated. Will he ever be able to have a relationship?