Religious folk - What are the most common leading questions you get from non-believers?

I hesitate to ask this but I am interested in your responses, that is why I am asking in General.

What questions are you tired of answering and re-answering? Ones that only lead to further argument?

Have you ever been asked a question that caught you by surprise, one you had never heard before?

Background: A evangelical gentleman on the radio was discussing his response to questions from atheists and evidently the second most common question they asked of him is “Where did Cains wife come from? He had two responses:
1) “I would answer that, If I were Able.” and
2) “God told Adam and Eve to be fruitful and multiply and this is what they did. Just like if you start out with two rabbits, you end up with a bunch of rabbits, Adam and Eve ended up with a bunch of kids. Cain married one of his distant sisters”.
Of the two answers I thought that the first was the best and I really did not understand his second one (what is a distant sister?).

Is this really the second most common question atheists ask you?
What is your answer to this question? What were you taught in Sunday School?

By the way, the most common was “Why is there suffering”.

Guys, please, no negative comments or arguing I want to know what the questions.