Did humans really go to the Moon?

There are a lot of people today who believe the whole thing was staged in in a film studio. Some say it was done on the set of 2001 and directed by Stanley Kubrick. This leads on to the matter that all space exploration is a hoax including the ISS, Mars rovers, the Hubble telescope and even satellites. Reasons given are: the Van Allen radiation belt, high temperatures and of course the crystal dome.