In designing a house, can a fireplace be put on the second floor if there is no fireplace beneath?

Can a fireplace be put on a second floor if there is no fireplace on the floor beneath?

As some of you may recall from previous questions, I am designing a house that isn’t likely to ever come into fruition. I was designing a house from my early teens to early twenties, and this is an adaptation of that one. It replicates sort of a Craftsman / Victorian farmhouse that has retained historical accuracy but has been tastefully renovated

My interest peaked again since the COVID lockdowns. Even though it won’t likely ever be built, it has become an obsession for me and I enjoy working on it.

Anyhow, On the ground level is a garage that is connected to the house. The main floor of the house is a few feet above the ground/garage level. Directly above the garage is a large, nicely-proportioned recreation / game room, accessible to the second floor. The main second floor is likewise a few feet above the game room level.

On the other side of a garage wall is a bathroom connected to a back office / bedroom on the main floor. On the other side of the game room is a bathroom connected to a master bedroom.

Obviously, neither the garage nor either bathroom on either floor needs a fireplace. But the recreation / game room, which is over the garage, would be greatly enhanced by a large fireplace (wood or gas) with an elevated hearth.

It seems ok to put an ashpit accessible to the garage. But it seems a little unusual to have a supporting chimney base on the ground and first floor to support a second-floor fireplace.

Is this arrangement plausible or practical? Have you ever known anything like this to be done?