How can I get a degree (masters or bachelors) in applied math or statistics?

I have been out of college for 20 years. I have a BA and I am working now, but I want to branch into the world of practical mathematics. Are there online or night classes for this sort of thing? Will I have to start all over and take calculus, etc from a community college? What are the good schools for this sort of thing? How hard is it to get in?