What do you say to your brother, who hasn't spoken to in 4 months?

My brother has shut us (my whole entire family, including extended family), out of his life after his wedding day. Although, he does speak to one of my mother’s brothers. Anyway, I live in a small town which is filled with everyones dirty secrets. My brother and i were extremely close, and after marrying a woman (from hell) he has not spoken to me in over 4 months. The things she did to rip him apart from our family are rediculous and unforgiveable. When i run into him i know for a fact SHE will be with him. I don’t think i will ever be able to look at her ever again for what she has put my family through. Therapists have told my mother he will come around, and that this woman is probably making his life a living hell. He was one of my best friends, someone i could tell the things i couldn’t tell to my best friends or my sister. I’m bound to run into him eventually, when this happens…What the hell am i supposed to say to him?