Does it matter to you if something is handmade?

How much, if at all, does knowing that something was done or made by hand add value for you? Businesses still use this as a marketing ploy (e.g. Panera Bread runs ads touting their “hand-tossed salads”), so it must carry some weight with some people. As we get better and better at the technology of manufacturing, does the involvement of the human hand matter more or less to you?