What's a funny web video series I can watch?

I don’t really follow online video all that much but I came across JakeandAmir.com a little while ago and love it as well as all the other CollegeHumor originals.

I also just saw The Guild won a ‘YouTube award’ and watched the whole 2 seasons in a day.

Any other web series (webisode? online video? what do you call these?) that are similarly irreverently funny and/or clever? Bonus for nerd humor.