Has anyone had any problems with talc as a filler in tablets?

My doctor has changed the brand of my blood pressure medication Losartan potassium. I have been taking Cozaar for a few years now and all was fine. Recently I was given same Losartan potassium manufatured by Teva which upset my system totally. The doctor then gave me the same but by Actavis and symptoms continued and maybe even were worse. Has anyone else had same symptoms, I looked at ingredients and they seem to contain talc and macrogol which Cozaar don’t. Has anyone else had problems?