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2davidc8's avatar

What do the statistical abbreviations HR, CI and P mean in clinical trial data?

Asked by 2davidc8 (10189points) December 26th, 2019

For example,
adjusted HR, 1.08; 95% CI, 0.85–1.36; P =.526

What are HR, CI and P, and what are they referring to?
I have a vague idea that they refer to probabilities and confidence levels, but what exactly?
And what is “adjusted”?

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6 Answers

elbanditoroso's avatar

HR = Hazard Ratio—> how dangerous is the thing being tested

P = Probability

I think you may mean CI (not CL) – which is Confidence Interval

See this

and this

elbanditoroso (33161points)“Great Answer” (2points) Flag as…
Pinguidchance's avatar

The Hazard Ratio is the chance of an event in one group compared with it’s likelihood in a second group. The regression model seeks to adjust for other factors which may influence results.

https://en.wikipedia.org/wiki/Hazard_ratio

Pinguidchance (5040points)“Great Answer” (1points) Flag as…
elbanditoroso's avatar

@Pinguidchance that was my first link in the response above.

elbanditoroso (33161points)“Great Answer” (0points) Flag as…
2davidc8's avatar

@elbanditoroso Yes, it’s CI, not CL. In this font, an upper case I looks exactly the same as a lower case L. Unfortunately, in Fluther, I don’t think I have a choice of font, do I?

Anyway, back to my original question, and looking at my example, is it saying that there is a 52.6% probability that that the Hazard Ratio of 1.08 is within that 95% Confidence Interval (since 1.08 is within the range of 0.85 to 1.36? And why “adjusted”? What is being adjusted?

2davidc8 (10189points)“Great Answer” (1points) Flag as…
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